If you’re looking to split your Vyvanse dose (for example, a single 60mg capsule into two 30mg doses), it’s possible to do so by dissolving the contents in water. Lisdexamfetamine is water-soluble, meaning the active ingredient will dissolve, while the inactive fillers may settle at the bottom.
How to split in water:
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Open the capsule and dissolve it in warm water—shake or stir well.
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For a basic split, you can use 16 oz (2 cups) of water. Drink 8 oz for a 30mg dose, then save the remaining 8 oz for later.
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For more precise control, use a measuring cup with mL markings. For instance, dissolving a 60mg capsule in 60 mL of water means each 1 mL = 1 mg. So, you could take 50 mL (50mg) in the morning and keep 10 mL (10mg) for a midday booster.
Important disclaimer: This isn’t medical advice. Always talk to your doctor before adjusting your medication. But if your insurance doesn’t cover multiple doses, this method may be worth discussing with your provider.