Vyvanse is a pro-drug which means it’s inactive until your body converts it into an active form.
Chemically, Vyvanse is made of:
Dextroamphetamine — the actual stimulant that affects the brain
L-lysine — a naturally occurring amino acid (used in protein building)
These two molecules are bonded together to form lisdexamfetamine.
Once Vyvanse is swallowed and digested, it’s absorbed into the bloodstream, still in its inactive form. After you take it:
- Enzymes in your red blood cells break apart the bond between the lysine and the dextroamphetamine.
- Once separated, dextroamphetamine is released and becomes active.
- The lysine is left behind, harmlessly processed like any other amino acid.
Other extended release amphetamines like Adderall XR usually consist of two beads in the capsule. Half are instant release, and the other half are time released. This can cause noticeable rush & crash side effects in people due to the varying concentrations of the drug in your bloodstream.
Benefits of Vyvanse:
Smoother onset: Because your body has to convert it first, Vyvanse takes about 90 minutes to kick in. This helps avoid the jarring “rush” some people feel with other stimulants.
Consistent effect: The conversion process happens at a steady rate, leading to stable blood levels and fewer ups and downs.
Long-lasting: One dose of Vyvanse can last up to 10-12 hours. This may vary depending on your metabolism and manufacturer of the drug.
Lower abuse potential: Since it has to go through digestion and enzymatic conversion, Vyvanse can’t be effectively snorted or injected. This makes it less likely to be misused compared to fast-acting stimulants.